Background: The factors influencing parents’ willingness to enroll their children in biobanks are poorly understood. This study sought to assess parents’ willingness to enroll their children, and their perceived benefits, concerns, and information needs under different consent and data-sharing scenarios, and to identify factors associated with willingness. Methods: This large, experimental survey of patients at the 11 eMERGE Network sites used a disproportionate stratified sampling scheme to enrich the sample with historically underrepresented groups. Participants were randomized to receive one of (...) three consent and data-sharing scenarios. Results: In total, 90,000 surveys were mailed and 13,000 individuals responded (15.8% response rate). 5737 respondents were parents of minor children. Overall, 55% (95% confidence interval 50–59%) of parents were willing to enroll their youngest minor child in a hypothetical biobank; willingness did not differ between consent and data-sharing scenarios. Lower educational attainment, higher religiosity, lower trust, worries about privacy, and attitudes about benefits, concerns, and information needs were independently associated with less willingness to allow their child to participate. Of parents who were willing to participate themselves, 25% were not willing to allow their child to participate. Being willing to participate but not willing to allow one’s child to participate was independently associated with multiple factors, including race, lower educational attainment, lower annual household income, public health care insurance, and higher religiosity. Conclusions: Fifty-five percent of parents were willing to allow their youngest minor child to participate in a hypothetical biobank. Building trust, protecting privacy, and addressing attitudes may increase enrollment and diversity in pediatric biobanks. (shrink)

The Principles of Biomedical Ethics by Beauchamp and Childress is a classic in the field of medical ethics. The first edition was published in 1979 and “unleashed” the four principles of respect for autonomy, non-maleficence, beneficence, and justice on the newly emerging field. These principles were argued to be mid-level principles mediating between high-level moral theory and low-level common morality, and they immediately became very popular in writings about medical ethics. Over the years Beauchamp and Childress have developed this approach (...) and vigorously defended it against the various criticisms that have been raised. The 5th edition of this book is, as all the …. (shrink)

The Principles of Biomedical Ethics by Tom L Beauchamp and James F Childress which is now in its fourth edition has had a great influence on the development of bioethics through its exposition of a theory based on the four principles: respect for autonomy; non-maleficence; beneficence, and justice (1). The theory is developed as a common-morality theory, and the present paper attempts to show how this approach, starting from American common-morality, leads to an underdevelopment of beneficence and justice, and that (...) the methods offered for specification and balancing of principles are inadequate. (shrink)

Corruption is consciously taking advantage of one's special position, power or wealth for personal gain. It is spreading because there is ignorance and absence of adequate knowledge on the subject and how to correct and control it. Added to this is the innocence of the believers in the infallibility of the legal, political, bureau cratic and other social systems. They become the victims of the exploiters of the system who know the system weaknesses and how to take advantage of it (...) for their personal gain. There are two levels of corruption—the grand corruption of those in power and the petty corruption of the lower levels. Corruption is a malady affecting both affluent and poor nations. while affluent nations do not exhibit much evidence of petty cor ruption, poor nations are subject to the effects of both grand and petty corruption from within their own bor ders and the effects of the grand corruption by the affluent. Social systems, value education, spiritual leam ing and character building are necessary to eradicate this cancer. (shrink)

(1884). ANNUAL ADDRESS READ BEFORE THE “SOUTH AFRICAN PHILOSOPHICAL SOCIETY,”. Transactions of the South African Philosophical Society: Vol. 4, No. 1, pp. xxx-liii.

There is a Mexican, as well as a Canadian version of the American Dream. What drives political idealism in Mexico is less the idea of individual right, or respect for the rights of communities, than it is the 'indigenous' right of an historically oppressed people to a political culture and life wholly their own.